Kyle Shanahan is considered one of the smartest offensive coaches in the NFL, but according to former NFL coach Jay Gruden, if there's one situation where the 49ers coach seems to struggle, it's when he's forced to call plays while his team is trailing.

SANTA CLARA, Calif. (KTXL) – 49ers head coach Kyle Shanahan meets with the media on Wednesday afternoon to update the status of wide receiver Deebo Samuel, who missed practice with a calf injury, welcoming back safety Talanoa Hufanga to his first full practice since suffering an ACL tear last season,

It’s remarkable how well Kyle Shanahan’s offense travels to other teams, and most impressive is the performance of 33-year-old quarterback Derek Carr.

The San Francisco 49ers offense takes another hit. Wide receiver Deebo Samuel is expected to miss “a couple weeks” after sustaining a calf strain late in Sunday’s 23-17 loss to the Minnesota Vikings, coach Kyle Shanahan said Monday.

The San Francisco 49ers have added defensive end Nick Bosa on the injury report ahead of their Week 3 matchup against the Rams. While the team hasn’t yet mentioned if he will play versus the Rams, Bosa was a limited participant in this week’s practice.