The Jaguars blew a franchise-record 19-point lead to the Houston Texans. How they respond will define their season.

In an important AFC South battle, the Houston Texans play host to the Jacksonville Jaguars on Sunday afternoon.

The Houston Texans’ 2025 season has been a losing proposition from the word “GO.” After getting off to an 0-3 start, with three close losses, they were able to cobble together a few wins, getting to 2-3, and 3-4 at various points in the season, but they have yet to climb to the .500 mark.

Check out the injury report for the Houston Texans (3-5), which has 15 players listed (including C.J. Stroud), as the Texans prepare for their matchup versus the Jacksonville Jaguars (5-3) at NRG Stadium, on Sunday, Nov. 9 at 1 p.m. ET.

Recent arrival and wide receiver Jakobi Meyers is expected to start in his first game with the Jacksonville Jaguars on his 29th birthday, Nov. 9, 2025.

The Jacksonville Jaguars (5-3) and the Houston Texans (3-5) meet Sunday in Week 10 at NRG Stadium in Houston, Texas. Kickoff is set for 1 p.m. ET (CBS). Let's analyze BetMGM Sportsbook's NFL odds around the Jaguars vs. Texans odds and make our expert NFL picks and predictions for the best bets.

Behind a 19-point comeback and a 26-0 fourth-quarter explosion from Davis Mills and the offense, the Texans secured a 36-29 victory in Week 10, moving to 4-5 on the season with eight games to play. Davis Mills, who filled in for the injured C.J. Stroud, secured the game-winning touchdown on a 14-yard scramble with 31 seconds remaining in the gam.

The Jaguars inactives for Week 10 are: wide receiver Brian Thomas Jr., running bac Cody Schrader, defensive tackle Austin Johnson, left guard Ezra Cleveland, tight end Hunter Long, and cornerback Jourdan Lewis.