Estrogen agonists/antagonists are compounds with tissue-selective actions. The pharmacological goal of these compounds is to produce beneficial estrogenic actions in certain tissues (e.g., bone and ...

Agonists vs. antagonists. (A) An unoccupied opioid receptor embedded in a cellular membrane. (B) An opioid receptor is bound to a natural agonist, for example, morphine. The drug binds causing a ...

Much excitement has built in recent years on the new class of incretin drugs that include glucagon-like-peptide-1 inhibitor (single agonists such as semaglutide) and also dual glucose-dependent ...

A sweeping review of dozens of clinical trials suggests that today’s most widely used GLP-1 receptor agonist drugs produce broadly consistent weight-loss results across age, race, ethnicity, and ...

Drugs like Ozempic, Wegovy and Mounjaro have been around for years, but they’ve recently been making headlines due to a rise in popularity as weight loss agents. They all belong to a class of drugs ...

When kids with ADHD need medicines to help with symptoms like hyperactivity, inattention, or impulsivity, doctors usually suggest stimulants first. But some children don’t respond well to these drugs ...

New drugs that spur weight loss and treat diabetes have been taking the public—and the pharmaceutical industry—by storm. The latest entrant, Zepbound, recently joined Ozempic, Wegovy, Victoza and ...

Opioid antagonists are medications people can take to treat opioid use disorder. They help by reducing withdrawal symptoms, addressing cravings, and managing overdoses. Doctors prescribe opioid ...

Stimulators of interferon genes (STING) are cytosolic sensors associated with the endoplasmic reticulum that respond to the presence of dsDNA in the cytosol, usually indicative of an invading pathogen ...