Fatty acid oxidation (FAO) disorders comprise a heterogeneous group of inborn errors of metabolism that impair the mitochondrial capacity to convert fatty acids into energy. These inherited conditions ...

The raw material for de novo fatty acid synthesis is acetyl-CoA, which can be obtained via the citrate shuttle pathway or from acetic acid. ACC and FASN catalyze the conversion of acetyl-CoA into ...

In a recent article published in the journal Molecular Psychiatry, researchers investigate the clinical relevance of long-chain polyunsaturated fatty acids (LC-PUFAs) in the underlying neuropathology ...

Metabolic Dysfunction-Associated Steatotic Liver Disease（MASLD） is characterized by excessive accumulation of lipids in hepatocytes and is closely associated with the rapid rise in insulin resistance, ...

How Do Short-Chain Fatty Acids Work? Your small and large intestines have a layer of cells that is called intestinal epithelium. When you eat more fiber, your body produces short-chain fatty acids to ...

John Kim receives funding from the National Institute of Health and Chest Foundation. Omega-3 fatty acids have garnered significant interest among patients and clinicians for their potential ...

Pensini et al. sought an efficient way to remove these contaminants. Using a combination of experiments and simulations, the researchers uncovered how fatty acids can help separate and trap pollutants ...