DNA does not float freely in the cell. Instead, it is wrapped around histone proteins to form structures called nucleosomes.

New findings shed light on how chromosomes manage the various pushing and pulling forces generated when cells divide. Specifically, researchers show that chromosomes resist being punctured by the ...

As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...

Accurate chromosome segregation and cell division are central to maintaining genomic integrity and ensuring proper development and tissue homeostasis. These processes rely on a complex network of ...

For sexual reproduction to yield healthy offspring, newly generated oocytes-immature egg cells-must receive the correct amount of DNA after cell division. This process of segregating chromosomes ...

Structure of Ndc80 complex bound to microtubule. Ndc80 complex is the major microtubule3binding module at the kinetochore. Green: α-tubulin, light-blue:β-tubulin, dark blue: HEC1 (a4subunit of the ...

The authors set out to answer a simple question. Do all chromosomes have the same chance of being mis-segregated during cell division? To address this, Klaasen and colleagues turned to several types ...

Processes such as wound healing, hair growth, and the continual renewal of cells all rely on cell division. In this process, chromosomes must be evenly distributed between two daughter cells. Even ...

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...

During cell division, chromosomes are duplicated and separated so that one copy of each chromosome is inherited by each of the two emerging daughter cells. Correct distribution of chromosomes requires ...

For a living cell to divide successfully, each daughter cell must inherit the correct genetic material. In eukaryotes, segregation of duplicated chromosomes is performed by the mitotic spindle, a ...