In a newly published article in Nature Genetics, researchers from the University of Chicago have identified tumor aneuploidy—an imbalance in the number of chromosomes—as a powerful biomarker ...

Stefan Fröhling, M.D., and Hartmut Döhner, M.D. The cause of chromosomal abnormalities remains poorly understood. Studies of various types of leukemia have shown that certain environmental and ...

Using a new technique, long-read sequencing, that allows DNA to be analyzed in much greater detail than before, a team of Swedish clinicians and researchers has discovered an unexpected complexity in ...

An AI tool identifies cells that can shed light on the earliest origins of cancer through a game of molecular ‘laser tag’. The human body relies on precise genetic instructions to function, and cancer ...

Human egg cells are often prone to chromosomal errors. As women age, the error rate increases sharply — and can contribute to infertility, pregnancy loss, and ...

A new study led by NYU Langone Health researchers found that cancer cells are better able to resist treatments when they have an abnormal number of chromosomes, which are DNA strands wound up in ...

The American College of Medical Genetics and Genomics (ACMG) has released a new Evidence-Based Clinical Practice Guideline (EBG), "Noninvasive prenatal screening for fetal chromosome abnormalities in ...

Researchers are investigating the potential of CRISPR in relation to Down syndrome.

More than two-thirds of early miscarriages seem to be due to abnormal chromosomes, the packages of DNA within all our cells, in the embryo or fetus. The remaining third are probably also largely due ...

“Therefore, EDA and aneuploidy rates represent two independent factors in determining the number of euploid embryos available for transfer and the overall likelihood of ART success.” “Therefore, EDA ...