Medical Dialogues

Dupilumab Effectively Controls Severe Atopic Dermatitis: Study Finds

A recent longitudinal cohort study found that dupilumab provides sustained, 12-month disease control for severe atopic ...
Lupus Science & Medicine

Incidence of serious infections, herpes zoster and hepatitis B virus reactivation among patients with SLE: a cohort study using a health claims database in Japan

Objectives To investigate the real-world incidence of serious infections (SI), herpes zoster (HZ) and hepatitis B virus (HBV) ...
BMJ

Do the associations of daily steps with mortality and incident cardiovascular disease differ by sedentary time levels? A device-based cohort study

4 Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Providencia, Chile 5 Universidad de Santiago de Chile (USACH), Escuela de Ciencias de la Actividad Física, el Deporte y la Salud, ...
BMJ

Clinical importance of simple muscular fitness tests to predict long-term health conditions: a systematic review and meta-analysis of 94 cohort studies

6 Health and Social Research Center, Universidad de Castilla La-Mancha, Cuenca, Spain Objective To examine the predictive validity of field-based muscular strength tests in relation to incident ...
ascopubs.org

Using Dose-Escalation and -Expansion Cohort Study as Pivotal Trial for Targeted Anticancer Drug Approval

BRCA1-Associated Protein 1 and Enhancer of Zeste Homolog 2: Pathway Interaction and Therapeutic Intervention in Breast Cancer, Mesothelioma, and Lymphoma Early-phase clinical trials (EPCTs) have been ...
Medical Dialogues

Montelukast use in Pregnancy not linked to Increased Risk of Congenital Malformations: Study

No increased risk of major congenital malformations was observed across any of the five asthma controller medication groups ...