Antisense oligonucleotides (ASOs) are small, single-stranded molecules that can suppress the expression of targeted genes and thereby achieve therapeutic effects. However, many ASO-based drug ...
Figure 1: The capacity available for E. coli gene expression can be indirectly measured to quantify burden. Figure 2: Relationships among capacity, growth rate and construct output for a combinatorial ...
Cells use feedback regulation to ensure robust growth despite fluctuating demands for resources and differing environmental conditions. However, the expression of foreign proteins from engineered ...
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