Researchers benchmarked nanopore methylation callers across bacterial, plant, mouse, and human datasets, comparing accuracy, ...

DNA methylation is a critical epigenetic mechanism in numerous biological processes, including gene regulation, development, ageing and the onset of various diseases such as cancer. Studies of ...

Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, has been published in Nature Communications.

Epigenetic clocks are important tools in modern aging research. Typically, they use characteristic DNA methylation patterns ...

In a recent study published in the journal Science Advances, researchers estimated the maximal longevity, gestation period, and sexual maturity age using deoxyribonucleic methylation (DNAm) by ...

DNA methylation is a highly studied epigenetic modification that is involved in regulating genome function and plays fundamental roles in development and disease. 1 It is linked to a broad range of ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

Semaglutide, the active ingredient in Ozempic and Wegovy, slowed multiple markers of biological aging by measurable margins ...