Pharmacodynamic interactions alter pharmacologic efficacy of a drug, although drug plasma levels remain unaltered. 2 This has an impact on either the pharmacologic efficacy or on the magnitude of side ...
For more than 20 years, the University of Washington has been home to a database built, maintained and expanded around the goal of helping to prevent health complications from adverse drug reactions, ...
Regulators, developers, and testing laboratories are exploring in silico models, transporter assays, and other options to better predict drug combination outcomes In the future, many drug–drug ...
Large language models (LLMs) can be broadly applied across multiple key stages in drug development: (1) Target identification and drug screening. Llama-Gram, GPCR LLM, and ProtChat systems effectively ...
A team of mathematicians and pharmaceutical scientists collaborated to identify the major cause of the low accuracy of the equation in the FDA guidance used to predict drug-drug interaction through an ...
Drug development of novel agents in NSCLC continues to evolve based on disease subtype identification and new pharmaceutical approaches. Molecular alterations in NSCLC that drive cancer growth have ...
If you take antiretroviral therapy (ART) to manage HIV, it’s common for your HIV drugs to have interactions with other medicines you take. Drug interactions are when medications taken together or ...
A drug interaction happens when a substance affects how a drug behaves in the body. Some substances that can cause interactions include other drugs, supplements, food, and alcohol. Drug interactions ...
A global team based out of the University of California, San Francisco (UCSF), has developed a new paradigm in COVID-19 drug development by focusing on the host as well as the virus. The researchers ...
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