Dynein is a minus-end-directed microtubule motor with critical roles in mitosis, membrane transport and intracellular transport. Several proteins regulate dynein activity, including dynactin 1, LIS1 ...

Movement signals life, and nowhere is this truer than inside a living cell. The millions of proteins and molecules within each of our cells bend, travel and conform in a complex but orchestrated ...

We describe the dynamics of kinetochore dynein–dynactin in living Drosophila embryos and examine the effect of mutant dynein on the metaphase checkpoint. A functional conjugate of dynamitin with green ...

Our cells rely on microscopic highways and specialized protein vehicles to move everything—from positioning organelles to carting protein instructions to disposing of cellular garbage. These highways ...

What is the dynein-dynactin complex and where is it found? What functions is this molecular motor thought to perform within cells? This is a macromolecular assembly is made up of two components, ...

Dr. Jonas Wilson, MD, Ing. Med. Dynein, one of three cytoskeletal motor protein families, was first identified a half century ago and got its name after the ‘dyne’ (i.e. a unit of force). Motor ...

Harvard – Molecular motors, built from proteins, are a kind of transport service that keep cells functioning. They traffic essential chemical packages between the heart of the cell, the nucleus, and ...

Oregon State University scientists have taken a key step toward better understanding neurodegenerative diseases by using a suite of biophysical techniques to learn more about a motor protein whose ...

Intracellular protein aggregation is a common theme in neurodegenerative disease. The formation of aggregates is blamed on protein overproduction, a failure of clearance, or both. Score one for the ...

Biologists have identified a new molecular player in asymmetric cell division, a regulatory protein named She1 whose role in chromosome- and spindle positioning wasn't known before. Asymmetric cell ...

Movement signals life, and nowhere is this truer than inside a living cell. The millions of proteins and molecules within each of our cells bend, travel and conform in a complex but orchestrated ...