It is well established that nutrients can stimulate the release of gut-peptide hormones, such as cholecystokinin (CCK), pancreatic polypeptide, peptide YY and glucagon-like peptide-1 (GLP-1), which ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 79, No. 14, [Part 1: Biological Sciences] (Jul. 15, 1982), pp. 4471-4475 (5 pages) In immunohistochemical studies ...

Adults who underwent duodenal mucosal resurfacing had improved glucose response and insulin sensitivity that suggest positive effects of the procedure on beta-cell function and the liver, according to ...

A potential new mechanism has been identified in both mice and human endocrine cells that populate the small intestines. Inside these cells is a protein called alpha-synuclein, which is known to go ...

Scientists show that endocrine stem cells in the pancreas disappear after birth, and detail the genetic identity of the different types of pancreatic hormone-producing cells. The pancreas is a key ...

Organoids—tiny, lab-grown 3D clusters of cells—are a useful tool for studying organ development, disease, and drug responses. These miniature organs-in-a-dish are powerful, but they’re not perfect: ...

Researchers have combined a drug that’s normally used to treat cancer with a naturally derived anti-inflammatory to stimulate pancreatic stem cells to grow into insulin-producing cells. The study’s ...

The pancreas is a wing-shaped gland that extends from the duodenum (the upper portion of the small intestine) to the spleen. It serves both digestive and endocrine functions. The pancreas aids in ...

The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is known to affect the elderly and those with coexisting chronic diseases such as obesity and diabetes more ...