Purpose. The effects of genetic polymorphisms on the pharmacokinetics of calcineurin inhibitors were examined. Pharmacogenetics examines the relationship between single-gene polymorphisms and the ...

Researchers at the University of Tsukuba have identified neurons that are essential for mice to engage in social interactions with novel individuals.

Precisely how lowered levels of the gene product, an enzyme called hexoseaminidase A, protect against TB isn't known. Balanced polymorphism may explain why cystic fibrosis is so common- the ...

Neuropsychiatric disorders are becoming increasingly prevalent. Given their complex and multifactorial pathogenesis, there is ...

investigated polymorphisms of the 5-HT transporter-linked promoter region (5-HTTLPR) gene. This gene has a short (S) allele and a long (L) allele; men with the LL genotype are likely to have ...

Balancing selection, in contrast to directional selection, maintains genetic polymorphism in populations. For example, if heterozygotes at a locus have higher fitness than homozygotes (a scenario ...

The studies revealed that polymorphisms were associated with susceptibility to periodontal diseases. In other word, genetic variations can change the development of CP. However, there are some ...

Prostate cancer is the second most common cancer affecting men globally, with diagnostic methods and risk assessment remaining a challenge despite decades of research. For years, the prostate-specific ...

Aims Clopidogrel is the most commonly prescribed thienopyridine as part of dual anti-platelet therapy for the treatment of ...

The part of DNA that determines what protein to produce and when, is called a gene. First established ... called restriction fragment length polymorphism. Because this process was extremely ...