Insulin resistance has a molecular fingerprint, and scientists have just cracked it. In a groundbreaking study, researchers from the University of Copenhagen found that each person’s body responds to ...

Taken together, our experimental paradigm in endothelial cells and VSMCs indicates that under normal conditions insulin is antiatherogenic. In endothelial cells, insulin stimulates NO production and ...

Insulin therapy can effectively control blood glucose levels in patients with diabetes. However, its use comes with the risk of inducing hypoglycaemia. Now, writing in Nature, Hoeg-Jensen et al. have ...

For more than a century, oral insulin has been considered a "dream" therapy for diabetes, hindered by enzymatic degradation ...

A new study focuses on the insulin receptor to understand its role in the development of type 2 diabetes mellitus, a metabolic disease with a major impact on global health. Insulin resistance precedes ...

An insulin that switches itself on and off in response to blood glucose levels has proven successful in lowering the risk of dangerously low glucose levels, or hypos, in animals. According to ...

Researchers revealed that the microbial metabolite TMA can directly block the immune protein IRAK4, reducing inflammation and improving insulin sensitivity. The molecule counteracts damage caused by ...

A small molecule made by gut microbes is rapidly emerging as one of the most intriguing new levers for controlling blood sugar and inflammation, hinting at a future in which diabetes care starts in ...

Insulin resistance is concomitant with type 2 diabetes, obesity, hypertension, and other features of the metabolic syndrome. Because insulin resistance is associated with cardiovascular disease, both ...