Neuroinflammation drives the progression of neurodegenerative disorders like Alzheimer's, Parkinson's, and multiple sclerosis ...

Malaria represents one of the most serious threats to human health worldwide, and preventing and curing this parasitic disease still depends predominantly on the administration of a small number of ...

Serendipity is to thank for several ground-breaking discoveries and treatments, such as Alexander Fleming’s accidental discovery of penicillin. 1 However, most drug breakthroughs stem from systematic ...

Understanding a drug’s mechanism of action (MOA) can greatly increase the likelihood of successful clinical trials by identifying biomarkers of patient response and providing a rationale for ...

A team from the University of Barcelona has designed and validated in animal models an innovative compound with a pioneering mechanism of action for the treatment of Alzheimer's disease. Unlike ...

Researchers are able to test in parallel the effects of over 1500 active substances on cell metabolism. Their analysis also led to the discovery of previously unknown mechanisms for known medications.

A collaborative research team has uncovered a previously unknown mechanism of action of yaku'amide B, a structurally complex peptidic natural product derived from deep-sea sponge found in the waters ...

Most of the oncology drugs that received the FDA’s accelerated approval from 2011 to 2020 had some kind of FDA postmarketing safety action, according to a research letter. Safety actions included ...