Microscopy image showing heart muscle cells (gray) in a mouse heart. The plakophilin-2 protein (green) is present in the desmosomes connecting adjacent heart muscle cells. After introduction of the ...
Surprisingly, already in our initial series of experiments, we have recognized unexpected changes in the molecular ensembles of cell–cell junctions of the adherens category. An especially eye-catching ...
A new study in mice suggests that gene therapy targeting plakophilin-2 can improve survival in people with arrhythmogenic right ventricular cardiomyopathy (ARVC). ARVC is a rare inherited disorder in ...
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