Advances in structural biology have allowed scientists to determine molecular structures with atomic-level detail, sometimes yielding static snapshots that do not reflect the dynamism of proteins.

Researchers from the University of Science and Technology of China (USTC), led by Prof. Liu Qi, in collaboration with Harvard Medical School's Marinka Zitnik lab, have developed a novel deep ...

Textbooks often depict proteins in one conformation, but real life, as usual, is much messier. While some proteins have stable, unchanging structures, many others have intrinsically disordered regions ...

A multicolored 3D model of an enzyme binding double-stranded DNA against a light purple background Computational enzyme design could allow for reactions not seen in nature. Credit: Ian Haydon ...

A new method that successfully designs serine hydrolase enzymes capable of catalyzing ester hydrolysis with high efficiency, demonstrates a computational approach for creating de novo enzymes that ...

Researchers recently published findings that could lay the groundwork for applying quantum computing methods to protein structure prediction. Researchers from Cleveland Clinic and IBM recently ...

For decades, scientists have relied on structure to understand protein function. Tools like AlphaFold have revolutionized how researchers predict and design folded proteins, allowing for new ...

The known protein universe just got a lot bigger. A newly released artificial-intelligence tool has generated an atlas of more than one billion predicted protein structures and billions more protein ...

AI2 Incubator’s Jenny Cronin (left), interviews David Baker, director of the University of Washington’s Institute for Protein Design. (GeekWire Photo / Charlotte Schubert) The Institute for Protein ...

Drug discovery happens to be among the most expensive and laborious processes across scientific disciplines. Developing just ...