Figure 2: Il23ra −/− T cells have lower IL-17 production after T cell priming. Figure 5: IL-23 promotes the effector cytokine profile of T H-17. Figure 7: Timing of the requirement for IL-23R during T ...
Following infection, naïve CD8⁺ T cells bearing pathogen-specific T cell receptors (TCRs) differentiate into a mixed population of short-lived effector and long-lived memory T cells to mediate an ...
Many G protein-coupled receptor-mediated responses desensitize within minutes. Sustained stimulation of µ-opioid receptors (MORs), which primarily signal through Gi/o proteins, leads to activation and ...