How do odorant receptors in the human nose recognize a wide variety of scent molecules? The structures of engineered versions of these receptors finally provide much-needed answers to this fundamental ...
Certain proteins found in the human brain have long been known to be critical to controlling how brain cells communicate with each other. So-called GABA A receptors are proteins that control the flow ...
A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled ...
New Cell-Based Assays Support Drug Discovery Across the Amylin Receptor Family STATE COLLEGE, PA, UNITED STATES, ...
The human olfactory system discriminates between thousands of odours by interacting specifically with olfactory receptors on sensory neurons. Each receptor can detect several odorants at different ...
Infectious diseases are illnesses caused by pathogenic microorganisms—including viruses, bacteria, fungi, and parasites—that invade a host, replicate, and ...
Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...
Scientists have found a way to fine-tune a central fat-control pathway in the liver, reducing harmful blood triglycerides ...
STRIvE-02: A First-in-Human Phase I Study of Systemically Administered B7-H3 Chimeric Antigen Receptor T Cells for Patients With Relapsed/Refractory Solid Tumors Overall, 262 patients with ER+/HER2– ...