Although all the patients did not exhibit identical symptoms, the scientists found nearly all of them had common complaints ...

Several labs will work with federal health authorities to develop a test for avian influenza, as the number of human cases ...

Gilead Sciences’ capsid inhibitor lenacapavir has the most competitive potential in long-acting combination regimens in HIV, ...

Allows identification of pathogenic organisms that are difficult to culture by detecting their DNA or RNA. A reverse transcriptase (RT) is an enzyme used to generate complementary DNA (cDNA) from an ...

A substance that acts against retroviruses such as HIV. There are several classes of antiretrovirals, which are defined by what step of viral replication they target: nucleoside reverse transcriptase ...

The four main classes, which most people are treated with, target one of three viral proteins which control HIV’s lifecycle: reverse transcriptase, integrase and protease. Historically, most people ...

The virus was further confirmed by means of reverse-transcriptase–polymerase-chain-reaction (RT-PCR) assay. The areas where surveillance of zoonotic pathogens was carried out are shown in orange.

Prime editing, a relative newcomer to the gene editing space, uses a modified Cas protein and a guide RNA to recruit a reverse transcriptase to a specific sequence on the target DNA strand. Although ...

Sequence variations in human immunodeficiency virus (HIV)-1 reverse transcriptase (RT) and protease, the molecular targets of anti-retroviral drug therapy, are prime examples of genes in which ...

Generally, the dual NRTI backbone treatment of combination with a non-NRTI (NNRTI) or protease inhibitor (PI) should comprise a cytidine analogue (lamivudine, emtricitabine) and a thymidine ...

CRF: Circulating recombinant form; NNRTI: Non-nucleoside reverse-transcriptase inhibitor; NRTI: Nucleos(t)ide analog reverse-transcriptase inhibitor. Eight nucleos(t)ide analog reverse ...