Rheumatoid arthritis (RA) is an autoimmune disease that affects millions worldwide and can have a devastating impact on patients' lives. Yet, about one in three patients respond poorly to existing ...
Foxp3⁺CD4⁺ regulatory T cells (Treg) have a crucial role in controlling CD4⁺ T-cell activation, proliferation, and effector function. However, the molecular mechanisms regulating Treg function remain ...
There are two types of Tph cells in rheumatoid arthritis joints that have different roles. Stem-like Tph cells live inside immune “hubs” called tertiary lymphoid structures, where they interact ...
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