Receptors are specialised membrane‐bound proteins that play a fundamental role in translating extracellular signals into precise intracellular responses. Integral to cellular communication, these ...

Glucocorticoid receptors (GRs) are ligand-activated transcription factors that play a pivotal role in mediating the effects of endogenous and synthetic glucocorticoids. These receptors regulate a ...

Edited by Karen Young Kreeger J.A. Bennett, R. Dingledine, "Topology profile for a glutamate receptor: Three transmembrane domains and a channel-lining reentrant membrane loop," Neuron, 14:373-84, ...

Although scientists can learn a lot from cell culture and animal models, they cannot truly substitute for all parts of the human body, especially the brain. But scientists have now used human brain ...

A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled ...

Turning a decades-old dogma on its head, new research from scientists at UC San Francisco and Stanford Medicine shows that the receptor for oxytocin, a hormone considered essential to forming social ...

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...

New Cell-Based Assays Support Drug Discovery Across the Amylin Receptor Family STATE COLLEGE, PA, UNITED STATES, ...

The research is a continuation of her 15 years of study of NMDA receptors and focuses on investigating how subtle changes in the receptor structure causes them to produce altered electrical signals.

"I think PAGER has potential for impact, both in the G protein coupled receptor biology field, and in synthetic circuits or cell-based therapies," said Alice Ting, professor of genetics at the School ...

Stress, the body's natural response to different types of challenges and daily problems, is an inherently harmless state experienced by most people worldwide. While short-term stress is a common ...