Antibiotic-resistant bacteria are dangerous because they already "know" what most antibiotics look like. Scientists at MIT have found a way to create something new: using generative AI to design two antibiotic compounds from scratch that can kill drug-resistant gonorrhea and MRSA in lab dishes and mice.

AI-designed antibiotics show in vivo efficacy against multidrug-resistant N. gonorrhoeae and MRSA, offering a new approach to combat AMR.

With help from artificial intelligence, MIT researchers have designed novel antibiotics that can combat two hard-to-treat infections: drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA).