TS gene promoter possesses regulatory tandemly repeated (TR) sequences that are polymorphic in humans, depending on ethnic factors. These polymorphisms have been reported to influence TS expression.
Assembling a comprehensive catalog of common human sequence polymorphisms is a key goal of the Human Genome Project. The International SNP Map Working Group has compiled a map of 1.4 million ...
The remaining 11 polymorphisms in TP53 are non-synonymous, resulting in an amino acid change in the protein. Only four of these polymorphisms have been validated by multiple submissions of the ...
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