ORCHARD PARK, N.Y. -- Running back James Cook got the Buffalo Bills on the board with a 46-yard rushing touchdown in the second quarter to cut the New England Patriots' lead in half. The touchdown drive came after a sluggish start for the Bills.

In Sunday’s 24-21 victory over the New England Patriots, the Bills trotted out a new personnel grouping for the first time this season.

Buffalo has talented players on both sides of the ball, as they are one of the most dominant teams in the AFC. Running back James Cook would be a perfect addition to the Patriots’ backfield, so he is my pick for this week’s Gimme Him player.

Josh Allen doesn't have to do it all, and may be hard-pressed to top 4,000 yards passing for a fifth consecutive season. And that’s not a bad thing.

The Buffalo Bills won a nail-biter against the New England Patriots, 24-21, in Week 16 action. The Bills, a massive 14.5-point favorite entering the game, struggled mightily to dominate their lowly divisional rivals.

Buffalo went down by two scores early in the game and needed to play from behind. Bills quarterback Josh Allen has been on a tear, scoring 10 touchdowns in his last three games. But the Patriots made it hard on him all afternoon. Allen was sacked for the first time since the Bills’ win over the Indianapolis Colts on Nov. 10.

A whole lot of running back James Cook and takeaways by the defense helped the Buffalo Bills erase an early 14-point deficit Sunday against the New England Patriots.

James Cook will lead the Buffalo Bills into their game versus the New England Patriots at Highmark Stadium on Sunday at 4:25 p.m. ET.The Patriots have been sputtering offensively, ranking

The Bills beat the Patriots 24-21 thanks to the performance from starting running back James Cook along with timely plays made by the defense. Cook ran the ball 11 times for 100 yards and one touchdown while also catching three passes for 26 yards and another touchdown, showing his ability to affect the game on the ground and through the air.

"Let Jimbo cook more often. Let Jimbo shake and sprint to the end zone. Let Jimbo gash through and dash by opponents. Let Jimbo run so Allen won’t have to as much on designed keepers. Cook is ready for the responsibility,

Buffalo Bills' running back James Cook breaks away from the New England Patriots' defense on an explosive 46-yard touchdown run. Dallas Cowboys cornerback DaRon Bland yanks a game-sealing takeaway from Tampa Bay Buccaneers running back Rachaad White's grasp.