Elsewhere, there are multiple NFL matchups featuring 2-0 teams, as the Vikings (+1.5) host the Texans and Steelers (-2.5) face the Chargers. All of the Week 3 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and NFL predictions you need to make the best Week 3 NFL picks now.

The Browns couldn't take advantage of the Giant opportunity. After Amari Cooper left the game with an undisclosed injury with 2:34 remaining, Cleveland was left with Deshaun Watson throwing a crossing pass to Cedric Tillman on fourth-and-4 from the Browns 44.

For much of the day, New York Giants, the team without the win coming into the game, looked like the better team. The scoreboard, when the day came to an end, reflected that fact in a 21-15 victory over the Browns.