Purpose. The effects of genetic polymorphisms on the pharmacokinetics of calcineurin inhibitors were examined. Pharmacogenetics examines the relationship between single-gene polymorphisms and the ...

Aims Clopidogrel is the most commonly prescribed thienopyridine as part of dual anti-platelet therapy for the treatment of ...

A single gene in the shorebird species known as ruffs controls the levels of testosterone in males, and this in turn affects ...

The purpose of this review is (1) to systematically present data relating AGTR1 gene polymorphisms in association with hypertension; and (2) to perform a meta-analysis of association studies of ...

Neuropsychiatric disorders are becoming increasingly prevalent. Given their complex and multifactorial pathogenesis, there is ...

The following is a summary of “High Density Lipoproteins Associate with Age-Related Macular Degeneration in the All of Us Research Program,” published in the January 2025 issue of Ophthalmology by ...

Groundbreaking study from researchers at The University of Texas Health Science Center at San Antonio uncovers genetic factor that may contribute to the risk of late-onset Alzheimer’s disease, a ...

Neuropsychiatric disorders are becoming increasingly prevalent. Given their complex and multifactorial pathogenesis, there is an urgent need for ...

Single nucleotide polymorphisms occur normally in human DNA and are the most common genetic variation. They occur when there is a difference in one nucleotide—the most basic unit of DNA.

They then integrated these findings with GWAS data on a European population of 25,032 individuals to identify genetic polymorphisms related to allergic sensitization. The research team found 18 ...

Researchers at the University of Tsukuba have identified neurons that are essential for mice to engage in social interactions with novel individuals.