PHYRAGO™ Represents the First and Only Improved Version of SPRYCEL® That Can Be Safely Co-administered With Gastric Acid-Reducing Agents TAIPEI, TAIWAN / ACCESSWIRE / January 15, 2025 / Handa ...

The World Health Organization discovered the cause of a mysterious disease outbreak in Congo: seasonal respiratory illnesses ...

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CYP2C19-mediated interactions Ticlopidine ↑ PPI effect Inhibition of omeprazole 5'-hydroxylation, decreased elimination Increased inhibition of gastric acid secretion Contraceptives ↑ PPI ...

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Omeprazole, the prototype drug of PPIs, is metabolized primarily by CYP2C19 to 5-hydroxyomeprazole. 5-hydroxyomeprazole is then transformed into 5-hydroxyomeprazole sulfone by CYP3A4. Omeprazole ...