CRF: Circulating recombinant form; NNRTI: Non-nucleoside reverse-transcriptase inhibitor; NRTI: Nucleos(t)ide analog reverse-transcriptase inhibitor. Eight nucleos(t)ide analog reverse ...

It is an ester-derived prodrug that is converted in vivo by serum and tissue esterases to tenofovir, an acyclic nucleoside phosphonate (nucleotide) that inhibits HIV reverse transcriptase.

Australia: A recent study published in Clinical Infectious Diseases has shown that the current use of integrase strand ...

If you enjoy eating red meat, you might want to pay attention to new research linking it to cancer risk. A recent study ...

More than 46,000 of them had been prescribed a form of HIV-suppressing medications known as reverse transcriptase (RT) inhibitors. Among this subgroup, Alzheimer's diagnoses occurred in about 2.5 ...

Sequence variations in human immunodeficiency virus (HIV)-1 reverse transcriptase (RT) and protease, the molecular targets of anti-retroviral drug therapy, are prime examples of genes in which ...

They use an enzyme called reverse transcriptase, just like the human immunodeficiency virus (HIV), to replicate themselves. Humans have evolved mechanisms to keep retrotransposons turned off most ...

The four main classes, which most people are treated with, target one of three viral proteins which control HIV’s lifecycle: reverse transcriptase, integrase and protease. Historically, most people ...

Specific subtypes and transmission clusters for HIV could require targeted interventions to control spread of HIV that is ...

Transposon Therapeutics, a biotechnology company developing a platform of novel, orally administered therapies for the treatment of neurodegenerative and aging-related diseases, including Alzheimer's ...

ElevateBio, LLC (ElevateBio), a technology-driven company focused on powering the creation of life-transforming genetic medicines, today appointed Amy Pooler, Ph.D., as Senior Vice President, Research ...