EurekAlert!15d
Machine learning-powered, high-affinity modification strategies for aptamers
Announcing a new publication for Acta Materia Medica journal. The binding affinity of aptamers to targets has a crucial role in the pharmaceutical and biosensing effects. Despite diverse ...
Armed robbery in Revesby14d
AI-Driven High-Affinity Strategies for Aptamer Modification
Despite diverse post-systematic evolution of ligands by exponential enrichment (post-SELEX) modifications explored in aptamer optimization, accurate prediction of high-affinity modification strategies ...
eLife7d
Interpretable Protein-DNA Interactions Captured by Structure-Sequence Optimization
The processed HT-SELEX data used in this study is from, 26 which contains processed DNA binding sequence motifs and their normalized copy number detected from the HT-SELEX experiment, referred to as M ...
C&EN16d
Aptamer-Antibody Birecognized Sandwich SERRS Biosensor in Accurate and Rapid Identification of Intraoperative Parathyroid Hormone
State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, College of Energy, Discipline of Intelligent Instrument and Equipment, Cancer Center and ...
C&EN29d
Post-Docking Refinement of Peptide or Protein-RNA Complexes Using Thermal Titration Molecular Dynamics (TTMD): A Stability Insight
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. RNA–protein ...
Frontiers26d
Harnessing nanotechnology for cancer treatment
Nanotechnology has become a groundbreaking innovation force in cancer therapy, offering innovative solutions to the limitations of conventional treatments such as chemotherapy and radiation. By ...