Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

After their offense went stagnant in Week 2 without one of their star performers, the San Francisco 49ers will look to ...

The San Francisco 49ers won't be making any changes to their starting lineup after one rookie made a big mistake in ...

By ROB MAADDI Pro Picks is a weekly column where AP Pro Football Writer Rob Maaddi shares his picks for upcoming games. For ...

DL Nick Bosa, WR Brandon Aiyuk and LB Fred Warner shared the team's mindset heading into the 2024 season, discussed the ...

If we recall all those seasons, all those stretches of games led by lackluster quarterbacks, backup quarterbacks or ...

NFL regular season began, the Dallas Cowboys made star quarterback Dak Prescott the highest-paid player in the league after ...

With all the injury issues and slow starts surrounding the 49ers' offense, former Super Bowl-winning quarterback Steve Young ...

Deebo Samuel revealed why teammate Brock Purdy was intimidated by him upon his arrival to the San Francisco 49ers in 2022.

Last season, Purdy had his best season yet finishing as a finalist for MVP where he threw for 4,280 yards to go with 31 touchdowns and 11 interceptions. He was voted captain for this season as 49ers ...

The 49ers QB became a better vocal leader this offseason. How will that help him overcome injuries to Deebo Samuel Sr. and ...

The San Francisco 49ers are dealing with some devastating early-season injuries to Deebo Samuel and Christian McCaffrey. It's ...