Gut

Luminal–basal stratification of the native human pancreatic duct is differentially represented in pancreatic cancers

Background A resemblance of pancreatic tumours to their native tissue architecture remains largely unexplored, while it may ...
Gut

Autoimmune gastritis: a hidden gateway to cardia and oesophageal cancers beyond non-cardia gastric adenocarcinoma

Autoimmune gastritis (AIG) has been traditionally recognised as a precursor to type I gastric neuroendocrine tumours and ...
gut.bmj

Mechanisms of intestinal adaptation in short bowel syndrome: what is the evidence?

Short bowel syndrome (SBS) is defined by a remaining small bowel length of less than 200 cm after surgical resection and is a condition with significant clinical implications and a high risk of ...
gut.bmj

Atypical diarrhea in an immunocompetent infant

A 2-month-old male infant was admitted with a 2-day history of cough and fever. Respiratory pathogen testing on admission confirmed influenza A (H1N1) virus infection. The patient was started on oral ...
gut.bmj

IDDF2025-ABS-0104 Lean MASLD: reclassification discrepancies, characteristics, and adverse liver outcomes across diverse populations

2 Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea, South 3 Department of Information Statistics, Andong National University, Andong-si, Gyeongsangbuk-do, Korea, ...
gut.bmj

Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration

Objective Intestinal epithelial cells (IECs) at the internal/external interface orchestrate the mucosal immune response. Paneth cells secrete antimicrobial peptides and inflammatory mediators, protect ...
gut.bmj

Early tumour necrosis factor antagonist treatment prevents perianal fistula development in children with Crohn’s disease: post hoc analysis of the RISK study

Background One in three children with Crohn’s disease develop perianal fistula complications (PFCs), among the most disturbing and difficult-to-treat disease-related complications. Retrospective ...
gut.bmj

Reticulon 3-mediated Chk2/p53 activation suppresses hepatocellular carcinogenesis and is blocked by hepatitis B virus

Correspondence to Dr Yuanyuan Ruan, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China; ryyfdu{at}126.com Objective ...
gut.bmj

Colon and rectal cancer survival in seven high-income countries 2010–2014: variation by age and stage at diagnosis (the ICBP SURVMARK-2 project)

Objectives As part of the International Cancer Benchmarking Partnership (ICBP) SURVMARK-2 project, we provide the most recent estimates of colon and rectal cancer survival in seven high-income ...
gut.bmj

The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications

4 Department of Hepatogastroenterology, Hopital Claude Huriez, CHRU Lille, France Correspondence to: Professor J-F Colombel Department of Hepato-Gastroenterology, Hopital Claude Huriez, CHRU de Lille, ...
gut.bmj

Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review

4 Department of Gastroenterology, Hepatology and General Medicine, Royal Adelaide Hospital, Adelaide, South Australia, Australia Correspondence to Dr Hashem B El-Serag, Section of Gastroenterology and ...
gut.bmj

Itopride in functional dyspepsia: results of two phase III multicentre, randomised, double-blind, placebo-controlled trials

Mayo Clinic College of Medicine, Department of Internal Medicine, Jacksonville, Florida, USA Background: Functional dyspepsia (FD) is a common disorder but there is currently little efficacious drug ...