Objective To investigate longitudinal brain atrophy in patients with neuromyelitis optica spectrum disorder (NMOSD). Methods We investigated the longitudinal brain atrophy rate in patients with ...

Background Anti-aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (AQP4Ab+NMOSD) is an inflammatory disorder of the central nervous system with relapse-dependent progression. Few ...

Objective The high degree of clinical overlap between atypical parkinsonian syndromes (APS) and Parkinson’s disease (PD) makes diagnosis challenging. We aimed to identify novel diagnostic protein ...

Background Patients with functional neurological disorders often report adverse physical events close to the onset of functional symptoms. However, the mechanism via which a triggering event may set ...

Background: One of the core clinical features of dementia with Lewy bodies (DLB) is extrapyramidal syndrome (EPS). Levodopa is currently the gold standard oral therapy for Parkinson’s disease (PD), ...

Objectives: To compare endovascular coiling with neurosurgical clipping of ruptured basilar bifurcation aneurysms. Methods: Patient and aneurysm characteristics, procedural complications, and clinical ...

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a commonly employed therapeutic procedure for patients with Parkinson's disease uncontrolled by medical therapies. This series ...

Objective To examine mortality and factors associated with survival in a population based multiple sclerosis (MS) cohort. Methods Clinical and demographic data of MS patients registered with the ...

Background: Past research shows that post-traumatic amnesia (PTA) duration is a particularly robust traumatic brain injury (TBI) outcome predictor, but low specificity limits its clinical utility.

OBJECTIVES To examine the relation between social deprivation and the prevalence of epilepsy and associated morbidity using hospital activity data as a proxy. METHODS The study was conducted in the ...

Twenty neurologists were asked to judge a number of plantar responses on film. Each film was preceded by a slide with a fictitious abstract of history and examination (minus the plantar reflex). The ...

Background New criteria for the neurophysiological diagnosis of amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) were recently proposed at an international symposium in Awaji-shima, Japan.