BACKGROUND: High-volume physical activity (PA) is associated with a higher prevalence of subclinical coronary artery disease ...

Cardiac fibroblasts (CF) can become activated and produce excessive extracellular matrix, contributing to fibrotic remodeling ...

Patients with an autoimmune or inflammatory disease (AIID) are at increased cardiovascular risk and may benefit more from statin therapy. In the FOURIER trial (Further Cardiovascular Outcomes Research ...

The growing morbidity, mortality, and health care costs related to heart failure (HF) underscore the urgent need to prioritize its primary prevention. Whereas a risk-based approach for HF prevention ...

Few middle-aged and older adults engage in regular leisure-time exercise. Incidental physical activity (IPA) encompasses activities of daily living outside the leisure-time domain. No dose-response ...

View all available purchase options and get full access to this article.

Cardiovascular disease remains a leading cause of morbidity and mortality in adults despite recent scientific advancements. Although people are living longer lives, there may be an adverse impact on ...

The SPRINT (Systolic BP Intervention Trial) compared an intensive systolic BP goal (<120 mm Hg) to a standard goal (<140 mm Hg). Carotid-femoral pulse wave velocity (PWV) was measured in a subset of ...

Request permissions for this article. Department of Medicine, UT Southwestern Medical Center, Dallas, TX (M.S.U.). Department of Medicine, Parkland Health and ...