Des Moines police are investigating a shooting that left one dead and another hospitalized on Christmas afternoon in an apparent domestic dispute.

The Des Moines Police Department asked the public on Christmas afternoon for help finding a 12-year-old girl. Nora Rash was ...

The announcement of his pick for ambassador comes after Trump threatened to reassert U.S. control over the Panama Canal.

A U.S. judge on Monday delayed a trial for the suspect in the second assassination attempt of President-elect Donald Trump ...

Someone’s Christmas wish might have been granted as the Mega Millions jackpot reached an estimated $1 billion for the Christmas Eve drawing. The last Mega Millions jackpot claimed was back on Sept. 10 ...

Peoria is abuzz with economic development, namely in its northern corridor, where the city wants to establish a hub for the semiconductor industry.

While Greenland is currently not for sale, the U.S. has purchased land and territories from other countries in the past.

USA TODAY goes to Wyoming's Wind River Reservation to hear the challenges and the pride of being indigenous in America.

Ten people were forced out of their Phoenix homes on Tuesday, Christmas Eve, after an apartment fire spread through four ...

Did you win the Mega Millions drawing on Christmas Eve? A jackpot of about $1 billion dollars is up for grabs. See the ...

Christmas has arrived, and whether you're looking to grab a cup of coffee, pick up some last-minute ingredients for your favorite holiday recipe, or shop for a new outfit to wear for Christmas dinner, ...

The United States Food and Drug Administration says the shortage of Eli Lilly’s Zepbound and Mounjaro drugs has been resolved ...