A bitter taste has always been considered a warning signal, devoted to protecting us from ingesting potentially harmful ...
Morning Overview on MSN
Scientists design opioids that ease pain with fewer dangers
Scientists are racing to redesign how powerful painkillers work, aiming to keep the relief that opioids provide while stripping away the worst dangers of addiction and overdose. Instead of tweaking ...
Members of the G protein-coupled receptors (GPCRs) superfamily mediate diverse biological processes upon activation by extracellular signals. Their important role in bone development, remodeling, and ...
Prostate cancer (PCa) is one of the most common cancers of male genitourinary system, with castration-resistant prostate cancer (CRPC) posing a major therapeutic challenge. G protein-coupled receptors ...
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BUFFALO, N.Y. – Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders.
Two different versions of the mu-opioid receptor within a cellular membrane illustrate how the receptor changes its conformation to send a signal into the cell. Scientists captured six high-resolution ...
Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), ...
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