Purpose. The effects of genetic polymorphisms on the pharmacokinetics of calcineurin inhibitors were examined. Pharmacogenetics examines the relationship between single-gene polymorphisms and the ...

Precisely how lowered levels of the gene product, an enzyme called hexoseaminidase A, protect against TB isn't known. Balanced polymorphism may explain why cystic fibrosis is so common- the ...

Researchers at the University of Tsukuba have identified neurons that are essential for mice to engage in social interactions with novel individuals.

investigated polymorphisms of the 5-HT transporter-linked promoter region (5-HTTLPR) gene. This gene has a short (S) allele and a long (L) allele; men with the LL genotype are likely to have ...

Balancing selection, in contrast to directional selection, maintains genetic polymorphism in populations. For example, if heterozygotes at a locus have higher fitness than homozygotes (a scenario ...

Neuropsychiatric disorders are becoming increasingly prevalent. Given their complex and multifactorial pathogenesis, there is ...

The studies revealed that polymorphisms were associated with susceptibility to periodontal diseases. In other word, genetic variations can change the development of CP. However, there are some ...

Late-onset Alzheimer's disease is a debilitating, progressive neurodegenerative disease that affects about 7 million Americans, a figure that is expected to nearly double by 2050, according to the ...

Aims Clopidogrel is the most commonly prescribed thienopyridine as part of dual anti-platelet therapy for the treatment of ...

The part of DNA that determines what protein to produce and when, is called a gene. First established ... called restriction fragment length polymorphism. Because this process was extremely ...

The following is a summary of “High Density Lipoproteins Associate with Age-Related Macular Degeneration in the All of Us Research Program,” published in the January 2025 issue of Ophthalmology by ...