DNA shape and rigidity regulate key players of gene expression

Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the ...
IEEE

Impact of Domain Knowledge and Multi-Modality on Intelligent Molecular Property Prediction: A Systematic Survey

Abstract: The precise prediction of molecular properties is essential for advancements in drug development, particularly in virtual screening and compound optimization. The recent introduction of ...
EurekAlert!

Revealing the molecular structures of sugars using galectin-10 protein crystals

A quick, purification-free method was developed by researchers at Institute of Science Tokyo, to capture the detailed 3D structures of flexible sugar molecules. By growing crystals of galectin-10 ...
C&EN

Structure and Mechanism of the Pyridoxal 5′-Phosphate-Dependent Amino Acid γ-Substitution Enzyme in 6-Alkyl-Pipecolate Biosynthesis

CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China CAS Key ...
C&EN

Genarris 3.0: Generating Close-Packed Molecular Crystal Structures with Rigid Press

Department of Materials Science & Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, United States Department of Materials Science & Engineering, Carnegie Mellon University, ...