Around 80 percent of proteins involved in diseases like cancer and neurodegenerative illnesses do not have a stable structure. These proteins, known ...

This study investigates the folding and unfolding behavior of the doubly knotted protein TrmD-Tm1570, providing insight into the molecular mechanisms underlying protein knotting. The findings reveal ...

Peptide bonds, also known as amide bonds, are the covalent chemical bonds that connect individual amino acids to form ...

Traditional live attenuated vaccines (LAVs) are typically developed through serial passaging or genetic engineering to introduce specific mutations or deletions. While viral RNA secondary or tertiary ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. RNA possesses functional significance that extends beyond the transport of genetic ...

The application of deep learning algorithms in protein structure prediction has greatly influenced drug discovery and development. Accurate protein structures are crucial for understanding biological ...

Announcing a new publication for Acta Materia Medica journal. Proteins are essential macromolecules that perform functions according to their conformational dynamics. Studying the conformational ...

Tertiary Lymphoid Structures (TLS) correlate with positive outcomes in patients with NSCLC and the efficacy of immune checkpoint blockade (ICB) in cancer. The actin regulatory protein hMENA undergoes ...