Houston Texans vs Arizona Cardinals
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Cardinals, Trey McBride
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Ole Miss head coach Lane Kiffin walks off the field during a college football game between Mississippi State and Ole Miss at Davis Wade Stadium in Starkville, Miss., on Friday, Nov. 28, 2025. The Egg Bowl game marks the 122nd meeting between the two teams. | Ayrton Breckenridge/Clarion Ledger / USA TODAY NETWORK via Imagn Images
Two players — running back Emari Demercado and rookie defensive lineman Walter Nolen — return to the lineup. Demercado missed the last three games with a high ankle sprain. Nolen missed the last two with a knee injury. WR Marvin Harrison Jr.
At 3-10, each of the Arizona Cardinals' roster holes can be connected to moves made by general manager Monti Ossenfort in free agency or the draft.
If you're playing in a superflex or two-quarterback league, you will have some tough decisions this week like starting Jacoby Brissett of the Arizona Cardinals.
The Cardinals activated second-year tackle Christian Jones. He had been on IR all season. With left tackle Paris Johnson out this week and Jonah Williams on injured reserve, it is possible he will start against the Texans. Either Jones or rookie Josh Fryar will start at one tackle spot with Kelvin Beachum on the other side.
The Cardinals fell to the Texans after a rough start, as the defense continued to struggle while Trey McBride shined.
Two weeks ago, the Arizona Cardinals spoke of the importance of a strong finish to the season. Instead, they've suffered two straight blowout losses.