Texas Tech alum and Kansas City Chiefs quarterback Patrick Mahomes joins the College GameDay set as the guest picker before a Big 12 Conference football game, Saturday, Nov. 8, 2025, at Jones AT&T Stadium. / Nathan Giese/Avalanche-Journal / USA TODAY NETWORK via Imagn Images

NFL Week 9 odds, picks, predictions, TV channel, streaming information for the Sunday football game between the Kansas City Chiefs and Buffalo Bills.

Both the Buffalo Bills and Kansas City Chiefs both tried to trade for multiple players, but deals were turned down at the last minute.

During the recent episode of New Heights, Kansas City Chiefs tight end Travis Kelce reflected on the Week 9 loss to the Buffalo Bills | @EdEastonJr

The Buffalo Bills continued their regular-season dominance against Andy Reid and the Kansas City Chiefs, winning 28-21 on Sunday.

This matchup features two storied franchises with ties to the early days of the American Football League (AFL). Buffalo was one of the inaugural members of the AFL in 1960, as were the Dallas Texans, who relocated to Kansas City and became the Chiefs after winning the 1962 AFL title.

There is no love lost between the Buffalo Bills fans and the team’s heated rival, the Kansas City Chiefs. The latest example of which came when the Chiefs hoppe

Buffalo Bills safety Cole Bishop delivered a bone-jarring hit on Chiefs tight end Travis Kelce, leading to Kelce being evaluated for a concussion.

Bills: The Buffalo Bills are the late 90s Chicago Bulls when it comes to beating the Kansas City Chiefs in the regular season. And they are pretty much whoever plays the Dodgers in the World Series against the Chiefs when it comes to the playoffs.

Entering Sunday’s Week 9 tilt between the Buffalo Bills and Kansas City Chiefs, there were many NFL observers who thought Kansas City’s high-octane offense would overwhelm Buffalo’s banged up defense, and that the Chiefs were the better team than the Bills.

Joey Bosa had his best game of the season in the Week 9 win over the Chiefs, showing that he's getting hot at the right time for the Buffalo Bills.