Objective To investigate longitudinal brain atrophy in patients with neuromyelitis optica spectrum disorder (NMOSD). Methods We investigated the longitudinal brain atrophy rate in patients with ...

With the increasing use of immune checkpoint inhibitors (ICIs), neurologists encounter more immune-related adverse events (irAEs). Since the mortality rate of encephalitis occurring as an irAE ...

Objective The high degree of clinical overlap between atypical parkinsonian syndromes (APS) and Parkinson’s disease (PD) makes diagnosis challenging. We aimed to identify novel diagnostic protein ...

In 2021, the National Institute for Health and Care Excellence produced an evidence-based guideline on the diagnosis and management of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a ...

Objective Myelin oligodendrocyte glycoprotein-associated disorders (MOGADs) are a rare new neurological autoimmune disease with unclear pathogenesis. Since a linkage of the disease to the human ...

Objectives To systematically review the efficacy and safety of anti-inflammatory agents for patients with major depressive disorders. Methods We searched the literature to identify potentially ...

Objectives To conduct an updated systematic review and meta-analysis of association between sleep and all-cause cognitive disorders. Methods PubMed and EMBASE were searched from inception to 18 ...

Background: One of the core clinical features of dementia with Lewy bodies (DLB) is extrapyramidal syndrome (EPS). Levodopa is currently the gold standard oral therapy for Parkinson’s disease (PD), ...

Lacunar stroke is a marker of cerebral small vessel disease and accounts for up to 25% of ischaemic stroke. In this narrative review, we provide an overview of potential lacunar stroke mechanisms and ...

From 1979-85, 2435 patients with a transient ischaemic attack or minor ischaemic stroke were randomly allocated to receive long term "blind" treatment with aspirin 600 mg twice daily (n = 815), ...

Objective Dysfunction of the blood–nerve barrier (BNB) plays important roles in chronic inflammatory demyelinating polyneuropathy (CIDP) and multifocal motor neuropathy (MMN). The aim of the present ...

Physical and pharmacological treatments can reduce pain and discomfort without compromising function Spasticity is a common symptom seen in many neurological conditions, notably head injury, spinal ...