What is lupus, and what does it do to your body? I just had a friend diagnosed with it after many months of tests. — T.S.B.

Cubs take series and open up a 6 1/2-game lead with a thunderous shutout, the Cardinals' fourth shutout loss in their past ...

Mexico midfielder Edson Álvarez celebrates after scoring as United States goalkeeper Matthew Freese reacts to the play in the ...

Chicago Cubs' Seiya Suzuki gestures after hitting a home run against the St. Louis Cardinals during the fifth inning of a ...

The winning numbers in Sunday's drawing of the "Missouri Cash Pop" game were: ...

BELLEVILLE — A man was charged in a shooting Thursday that left a 4-year-old boy wounded, according to police.

The death toll from flash floods that raged through central Texas rose to 70 after searchers found more bodies.

It is Donovan's first All-Star honor as he is the lone representative (thus far) for the Cardinals. He was elected by his ...

St. Louis City SC lost its third game in a row and is winless in five games after falling to Real Salt Lake 3-2, making their ...

ST. LOUIS — Officers arrested over a dozen people Saturday night into the wee hours of Sunday morning in the downtown area ...

Erick Fedde and the St. Louis Cardinals face the Chicago Cubs on Sunday in the rubber game. Here's how to watch and listen.

The class action lawsuits filed this week claim St. Louis' and St. Louis County's senior property tax freeze programs don't ...