Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation and is also an effective vasodilator.

Prostacyclin, a prostanoid metabolized from endogenous arachidonic acid through the cyclooxygenase (COX) pathway, is a potent vasodilator that has been identified as one of the most effective drugs for …

Prostacyclin refers to a member of the endogenous prostanoid family that is produced from arachidonic acid. It is released by pulmonary artery endothelial cells in the pulmonary circulation and binds to a …

Jul 25, 2025 · Prostacyclin, also known as prostaglandin I2 (PGI2), is a naturally occurring lipid molecule within the human body. This potent substance serves as a regulator within the circulatory system, …

Prostacyclin was discovered in the 1970’s by Sir John Vane, who eventually won the Nobel prize in Medicine for his discovery and understanding of prostaglandin and its physiological effects. But it …

Jul 13, 2024 · Prostacyclin or Epoprostenol: -> used in the treatment of RV failure and pulmonary hypertension

Prostacyclin carries out several important actions to help maintain proper heart and lung function. Prostacyclin deficiency has been linked with increased pulmonary arterial pressure, disease severity, …

Prostacyclin (PGI 2) is a product of arachidonic acid metabolism within vascular endothelium and is a potent vasodilator.

May 13, 2011 · Prostacyclin (PGI 2) is a member of the prostaglandin family of bioactive lipids. Its best-characterized role is in the cardiovascular system, where it is released by vascular endothelial cells, …

Prostacyclin is a potent vasodilator and an inhibitor of platelet aggregation, produced mainly by the endothelial cells lining the blood vessels. It plays a crucial role in hemodynamics by helping regulate …