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Oct 30, 2024 · The Web's Daily Resource for Lupus News
1st patient enrolled in global Phase 2 trial of daxdilimab for...
May 18, 2023 · A Phase 2 trial evaluating the safety and efficacy of daxdilimab, a potentially first-in-class treatment for people with active, proliferative lupus nephritis (LN) — a lupus complication marked by kidney damage — has enrolled its first patient.
Federal grant aims to get more Black patients into lupus clinical trials
Dec 21, 2023 · Lupus Foundation of America awarded 3-year grant worth $500K per year. by Mary Chapman December 21, 2023. The Lupus Foundation of America (LFA) will use a three-year federal grant — worth up to $500,000 per year — to continue efforts to increase the number of Black lupus patients in the U.S. who participate in clinical trials.
FDA updates Lupkynis label to include long-term efficacy data
May 6, 2024 · The U.S. Food and Drug Administration (FDA) has updated the prescribing label for Lupkynis (voclosporin), which is approved to treat a severe manifestation of lupus called lupus nephritis, to include data that shows it continues to safely preserve kidney function for up to three years. The data came from AURORA 2 (NCT03597464), a two-year ...
LRA awards scientists $600K for work into new treatments for lupus
by Mary Chapman March 14, 2024. The Lupus Research Alliance (LRA) has announced the latest recipients of its Lupus Mechanisms and Targets Award (LMTA), who will investigate molecular pathways or targets that could lead to new or better treatments for lupus. Each of the seven awarded scientists will receive up to $600,000 in funding over three ...
1st lupus patient treated with CAR T-cell therapy FT819 in early trial
May 16, 2024 · A 27-year-old woman with hard-to-treat systemic lupus erythematosus (SLE), the most common type of lupus, became the first patient treated in an early clinical trial evaluating FT819, Fate Therapeutics’ off-the-shelf CAR T-cell therapy candidate. The Phase 1 study (NCT06308978), taking place at the University of Minnesota Medical School and ...
Lupkinis plus MMF most effective as treatment for lupus nephritis
by Andrea Lobo, PhD January 8, 2024. A combination of Lupkinis (viclosporin) with mycophenolate mofetil (MMF) was the most effective at managing lupus nephritis, according to a systematic review of clinical trial data. The treatment was also associated with the highest risk of infections and serious infections, indicating a lower safety profile ...
Lupus overview - Lupus News Today
Feb 9, 2023 · Lupus is a chronic disorder wherein the immune system attacks the body’s own healthy tissue. Lupus can affect virtually every part of the body, including the skin, kidneys, joints, brain, heart, and lungs, resulting in a range of symptoms. Systemic lupus erythematosus (SLE) — often referred to simply as lupus — is the most common and ...
When the ‘ugly-wuggly’ signs of a lupus flare start peeking out
Apr 3, 2024 · But nothing stops the bounce in my stride quite like the first signs of a lupus flare peeking out for the world to see. Then, the invisible survivor-warrior-lupie-spoonie-victor turns into an unmistakable host, someone controlled by the disease. I slowly start to emit the ugly-wugglies of lupus. Last month was plagued by the uglies, even though ...
2 New Meds Found to Change Lupus Nephritis Treatment: Report
Jan 23, 2023 · Still many patients on high-dose corticosteroids, report finds. The analysis included data from 962 people with the disease in the U.S., as well as insights from 138 rheumatologists — autoimmune disease specialists — and 104 nephrologists, or kidney specialists.